INTEGRATED SINGLE-CELL AND BULK RNA SEQUENCING REVEALS CREM IS INVOLVED IN THE PATHOGENESIS OF ULCERATIVE COLITIS

Integrated single-cell and bulk RNA sequencing reveals CREM is involved in the pathogenesis of ulcerative colitis

Background: Ulcerative colitis (UC) is an inflammatory bowel disease characterized by persistent colonic inflammation.Here, we performed a systematic analysis to gain better insights into UC pathogenesis.Methods: Pet Supplies We analyzed two UC-related datasets extracted from the gene expression omnibus database using several bioinformatics tools.T

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Exfoliation Corrosion and Pitting Corrosion and Their Role in Fatigue Predictive Modeling: State-of-the-Art Review

Intergranular attack (IG) and exfoliation corrosion (EC) have a detrimental impact on Cereal the structural integrity of aircraft structures of all types.Understanding the mechanisms and methods for dealing with these processes and with corrosion in general has been and is critical to the safety of critical components of aircraft.Discussion of case

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Real-Time Co-Simulation and Grid Integration of PMSG-Based Hydrokinetic Energy Conversion Systems via Power-Hardware-in-the-Loop Technics

Ocean energy sources are a promising source of energy.However, simulating a hydrokinetic farm with multiple units requires significant computational resources, while physical Cloth experimentation on site is expensive.Therefore, the scientific challenge is to develop analytical and experimental tools that consider real aspects of areas with generat

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Role of the Combination of Cyclin-Dependent Kinase Inhibitors (CDKI) and Radiotherapy (RT) in the Treatment of Metastatic Breast Cancer (MBC): Advantages and Risks in Clinical Practice

Targeting cell cycle has become the gold standard for metastatic breast cancer (MBC), being cyclin-dependent kinase inhibitors (CDKIs) cornerstones of its treatment, alongside radiotherapy (RT).To date, no definite evidence regarding safety and efficacy of the combination of CDKIs plus radiotherapy (RT) Cereal is currently available.Purpose of this

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